What is NitrAdine®?

NitrAdine® is a unique tablet formulation. When dissolved in lukewarm water, it will result in a highly active solution that removes pathogenic biofilm from teeth, gums and implant materials to clinically insignificant levels.

The mode of action of NitrAdine®’s efficacy is based on the combination of a high concentration of surfactant (SLS) and other ingredients. The surfactant denatures the biofilm/micro-organism membrane proteins, whilst the other ingredients result in a slow release of a non-toxic concentration of only 0.02% hypochlorite, killing all micro-organisms (bacteria, fungi and viruses) present within the biofilm. (NitrAdine® is not hypochlorite. Hypochlorite, also called bleach, is a 2-10% concentration of NaOCI, which is toxic and cannot be used in the mouth).

Several independent academic in-vitro studies have demonstrated that NitrAdine® induces a significant reduction of biofilm formed by Candida albicans, Staphylococcus aureus, Streptococcus mutans and Pseudomonas aeruginosa on oral medical devices . In addition, an anti-viral activity against Herpes simplex was observed (Ref 1-8). Recent clinical studies in patients suffering from chronic periodontitis demonstrated that 10 days brushing with PerioTabs® induces a significant reduction of periodontopathogenic bacteria including Porphyromonas gingivalis, Provotella intermedia and Aggregatibacter actinomycetemcomitans(Ref 9). NitrAdine® also reduces microorganisms present on toothbrush heads.


Additional properties of NitrAdine® :

  • Non-toxic to gums (non-irritating, non-sensitizing)
  • Non-antibiotic
  • Non-corrosive to metal implants
  • Non-erosive to dentine or enamel
  • Compatible with all toothbrush heads